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April 24, 48 comments Methylation is a biochemical process that builds neurotransmitters like dopamine and serotonin, produces energy, processes hormones, builds immune cells, turns genes on and off, synthesizes DNA, Titration hypothesis the protective coating on your nerves and transforms toxins into safer substances.
Chemically speaking, methylation describes the addition of a methyl group to a substrate source material thereby producing a new chemical.
Sometimes instead of simply adding a methyl group, some other atom or group in the substrate is replaced. Methylation happens in all the cells of your body distributing methyl CH3 groups to as many as 50 or more other chemical processes in the body.
Each of these is a potential weak link which may hobble your methylation cycle because of deficient diet, genetic mutation, toxic exposure, high stress, virus, infection or any combination of those. Every can of tuna, every plastic bag, Styrofoam cup, cleaning product and consumer product you touch is introducing chemicals into your blood that were unknown years ago.
Methylation is catalyzed by enzymes which are fragile and easily damaged by toxins like heavy metals especially mercury. Here is an explanation of how Mercury may be related to vitamin B12 and thus methylation written by Christina Bolander-Gouaille: Well, there may well be some important links.
The monovalent cobalt atom in methyl B12 is readily oxidized by various compounds — for instance nitrous oxide.
This oxidation inactivates methioninsyntase MS which has then to be formed de novo. Mercury, as we know, does oxidize many compounds, logically also cobalt. This in turn is one explanation of why symptoms of mercury overload and vitamin Bdeficiency may be identical!
There is also a second possible interaction between vitamin B12, and mercury. High doses of vitamin B12, that overcome the block to some extent, has had sometimes stunning results in these conditions. Cooney also states that moderate exercise is important for better methylation.
He too warns against strenuous exercise such as marathon running, which has been found to decrease the levels of choline, among other things.
Moderate exercise, however, is vital for improving circulation. Good circulation, in turn, insures better handling of homocysteine. Cooney recommends exercise that is sufficiently vigorous to make a person sweat, and one that alternately dilates and constricts blood vessels in the extremities.
Sauna followed by cooling down has a similar effect.
Cooney mentions that massage likewise enhances circulation.Titration is the slow addition of one solution of a known concentration (called a titrant) to a known volume of another solution of unknown concentration until the reaction reaches neutralization, which is often indicated by a color change.
Many of the suggestions below involve the use of animals. Various laws apply to the use of animals in schools particularly any "live non-human vertebrate, that is fish, amphibians, reptiles, birds and mammals, encompassing domestic animals, purpose-bred animals, livestock, wildlife, and also cephalopods such as octopus and squid".
Glossary of Biological Terms ← BACK. A abdomen.
In vertebrates, the portion of the trunk containing visceral organs other than heart and lungs; in arthropods, the posterior portion of the body, made up of similar segments and containing the reproductive organs and part of the digestive tract.
The muscle proteins. The total amount of muscle proteins in mammals, including humans, exceeds that of any other protein. About 40 percent of the body weight of a healthy human adult weighing about 70 kilograms ( pounds) is muscle, which is composed of about 20 percent muscle protein.
Thus, the human body contains about 5 to 6 kilograms (11 to 13 pounds) of muscle protein. Attention: As we update our core systems, key features of the website including ordering and real-time price and availability, may be unavailable for China, India, Korea and Singapore from Friday evening, November 9th until Sunday morning November 11th.
Finally, here is the summation of methylation written by Viking that got me started on this journey. Note that I’ve changed the timing of the Folate & B12 dosing based on Dr. Lynch‘s comments in the video (folate-first causes unpleasant side effects).
Methylation is a central and vital process in the whole body and if this get’s disturbed, all sorts of things go wrong.